Determination of clofibrate in biological fluids by thin-layer and gas-liquid chromatography.
نویسندگان
چکیده
A specific and sensitive method is described for the detection of clofibrate in biological fluids. The drug is separated from associated fatty acids by thin-layer chromatography and the methyl ester is quantified by gas-liquid chromatography. Recovery is excellent, and any small losses are corrected with an internal recovery standard. Although more time-consuming than other available techniques, the method offers advantages for accurate studies of clofibrate metabolism.
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ورودعنوان ژورنال:
- Journal of lipid research
دوره 15 4 شماره
صفحات -
تاریخ انتشار 1974